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CanCURE

The Canadian HIV Cure Enterprise (CanCURE) is a research collaboratory focused on studying HIV persistence during antiretroviral therapy and developing strategies towards a sustainable HIV remission. Our innovative scientific program is supported by the Canadian Institutes of Health Research (CIHR).

CanCURE Photo Gallery

Available Positions

Research Assistant or Associate

Available at the Research Institute of McGill University Health Centre (RI-MUHC) to work on CIHR-funded research studies on HIV immunology. The candidate will be supervised by Dr Cecilia Costiniuk, Associate Professor in Infectious Diseases at McGill.

 

Postdoctoral Fellow 

Available at the Research Institute of McGill University Health Centre (RI-MUHC) to work on CIHR-funded research studies on HIV immunology. The candidate will be supervised by Dr Cecilia Costiniuk, Associate Professor in Infectious Diseases at McGill.

 

Postdoctoral Fellow

Human Immunodeficiency Virus (HIV)-host interactions governing HIV persistence in different models of humanized mice. Dr. Eric Cohen, Montreal Clinical Research Institute (IRCM, Montreal)

Publications

Jain et al. Bivalent SMAC mimetic APG-1387 reduces HIV reservoirs and limits viral rebound in humanized mice. iScience. November 2024

Ikeogu N, Ajibola O, Zayats R, Murooka TT. Identifying physiological tissue niches that support the HIV reservoir in T cells. mBio. September 2023
 
Clain et al. Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques. JCI insight. July 2023
 
Gantner et al. HIV rapidly targets a diverse pool of CD4+ T cells to
establish productive and latent infections.
Immunity. March 2023

Colas et al. Generation of functional human T cell development in NOD/SCID/IL2rγnull humanized mice without using fetal tissue: Application as a model of HIV infection and persistence. Stem Cell Reports. February 2023

Fert et al. Targeting Th17 cells in HIV-1 remission / cure interventions. Trends in Immunology. July 2022

Tremblay et al. Bryostatin-1 Decreases HIV-1 Infection and Viral Production in
Human Primary Macrophages.
Journal of Virology. February 2022

Murooka et al. T cell migration potentiates HIV infection by
enhancing viral fusion and integration.
Cell Reports. February 2022

In Memory of Ron Rosenes

1947-2023

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